Expresión de búsqueda: SEQUESTOSOME-1 PROTEIN 
Descriptores Encontrados: 1
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Descriptor Inglés:   Sequestosome-1 Protein 
Descriptor Español:   Proteína Sequestosoma-1 
Descriptor Portugués:   Proteína Sequestossoma-1 
Sinónimos Inglés:   EBI3 Associated Protein of 60 KDa
EBI3-Associated Protein of 60 KDa
EBIAP Protein
Phosphotyrosine Independent Ligand For The Lck SH2 Domain Of 62 Kda
Phosphotyrosine-Independent Ligand For The Lck SH2 Domain Of 62 Kda
Sequestosome 1 Protein
Ubiquitin Binding Protein p62
Ubiquitin-Binding Protein p62  
Categoría:   D12.644.360.024.329
D12.776.094.750
D12.776.157.057.160
D12.776.476.024.422
Definición Inglés:   A multidomain protein that is highly conserved among multicellular organisms. It contains a ZZ-type ZINC FINGER domain, C-terminal UBIQUITIN - associated (UBA) domain, and interacts with many other signaling proteins and enzymes including, atypical PROTEIN KINASE C; TNF RECEPTOR-ASSOCIATED FACTOR 6; subunits of the mTORC1 complex, and CASPASE-8. It functions in AUTOPHAGY as a receptor for the degradation of ubiquitinated substrates, and to co-ordinate signaling in response to OXIDATIVE STRESS. 
Nota Histórica Inglés:   2017 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   56538 
Identificador Único:   D000071456 

Ocurrencia en la BVS:
 

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